<![CDATA[IGF-1 and growth factor peptides — the growth mechanism explained]]>Insulin-like Growth Factor 1 is probably the most powerful growth signaling molecule in human biology. It mediates much of the body's growth hormone activity and is directly responsible for tissue growth in muscle, bone, and other tissues. The peptide community interest in IGF-1 LR3 (a long-acting analog) and Mechano Growth Factor (MGF) for enhancement comes from this growth mechanism.

The serious honest assessment:

IGF-1 causes growth — in tissues that are responsive to it. Muscle tissue is exquisitely IGF-1 responsive. Penile smooth muscle and corpus cavernosum tissue? Limited research. Some laboratory evidence of IGF-1 receptor expression in penile tissue. Whether exogenous IGF-1 produces meaningful enhancement — there is essentially no human evidence.

The risks of systemic IGF-1 elevation are also significant: hypoglycemia, acromegaly features, potentially increased cancer cell proliferation. This is not a casual experiment.

— IGF1_Ian

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